Kinase profiling results of kinases in KIF 2EVAA_ADN (MAP3K7, PDB code: 2EVA, chain A)
Template Kinase: MAP3K7
Template inhibitor: Vidarabine

 6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
GRK1AGC
CDK2CMGC
EGFRTK
RETTK
MAP3K7TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
GRK6AGC 
CDK2CMGC 
EGFRTK 
RETTK 
MAP3K7TKL