Kinase profiling results of kinases in KIF 3RHXA_3RH (FGFR1, PDB code: 3RHX, chain A)
Template Kinase: FGFR1
Template inhibitor: 6-o-tolylquinazolin-2-amine

 27 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
MAPK14CMGC 
MAP4K4STE 
ABL1TK 
TNK2TK 
CSKTK 
EGFRTK 
EPHA4TK 
EPHA5TK 
EPHA6TK 
EPHB1TK 
EPHB2TK 
EPHB3TK 
EPHB4TK 
FGFR1TK 
FGFR2TK 
JAK2TK 
JAK3TK 
RETTK 
FYNTK 
SRCTK 
YES1TK 
LCKTK 
PTK6TK 
TEKTK 
KDRTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
MAPK14CMGC   
MAP4K4STE   
ABL1TK   
CSKTK   
EGFRTK   
EPHA4TK   
EPHA5TK   
EPHA6TK   
EPHB1TK   
EPHB2TK   
EPHB3TK   
EPHB4TK   
FGFR1TK   
FGFR2TK   
FYNTK   
JAK2TK   
JAK3TK   
KDRTK   
LCKTK   
PTK6TK   
RETTK   
SRCTK   
TEKTK   
TNK2TK   
YES1TK