Kinase profiling results of kinases in KIF 1TVOA_FRZ (MAPK1, PDB code: 1TVO, chain A)
Template Kinase: MAPK1
Template inhibitor: FR-180204

9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PDPK1AGC 
RPS6KB1AGC 
CHEK1CAMK 
CDK2CMGC 
GSK3ACMGC 
MAPK1CMGC 
EIF2AK2Other 
SRCTK 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
PDPK1AGC     
RPS6KB1AGC     
CHEK1CAMK     
CDK2CMGC     
GSK3ACMGC     
MAPK1CMGC     
LCKTK     
SRCTK