Kinase profiling results of kinases in KIF 1PMNA_984 (MAPK10, PDB code: 1PMN, chain A)
Template Kinase: MAPK10
Template inhibitor: 1pmn

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK3CMGC
CDK5CMGC
CDK9CMGC
CLK4CMGC
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
MAPK14CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK3CMGC     
CDK5CMGC     
CDK9CMGC     
CLK4CMGC     
MAPK10CMGC     
MAPK14CMGC     
MAPK8CMGC     
MAPK9CMGC