Kinase profiling results of kinases in KIF 3PTGA_932 (MAPK10, PDB code: 3PTG, chain A)
Template Kinase: MAPK10
Template inhibitor: N-[4-Methyl-3-(1h-1,2,4-Triazol-5-Yl)thiophen-2-Yl]-2-(2-Oxo-3,4-Dihydroquinolin-1(2h)-Yl)acetamide

5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
AURKAOther
AURKBOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
AURKAOther
AURKBOther