Kinase profiling results of kinases in KIF 1BMKA_SB5 (MAPK14, PDB code: 1BMK, chain A)
Template Kinase: MAPK14
Template inhibitor: SB-218655

14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKD3CAMK
CDK2CMGC
GSK3BCMGC
MAPK10CMGC
MAPK9CMGC
NLKCMGC
MAPK11CMGC
MAPK14CMGC
CHUKOther
ABL1TK
FGFR1TK
SRCTK
LCKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PRKD3CAMK    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
GSK3BCMGC    
MAPK10CMGC    
MAPK11CMGC    
MAPK14CMGC    
MAPK9CMGC    
NLKCMGC    
CHUKOther    
ABL1TK    
FGFR1TK    
LCKTK    
SRCTK