Kinase profiling results of kinases in KIF 1KV2A_B96 (MAPK14, PDB code: 1KV2, chain A)
Template Kinase: MAPK14
Template inhibitor: Doramapimod

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C
MAPK9CMGC     
MAPK11CMGC     
MAPK14CMGC     
ABL1TK     
ABL2TK     
SRCTK     
YES1TK     
LCKTK     

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
MAPK11CMGC   
MAPK14CMGC   
MAPK9CMGC   
ABL1TK   
ABL2TK   
LCKTK   
SRCTK   
YES1TK