Kinase profiling results of kinases in KIF 1M7QA_DQO (MAPK14, PDB code: 1M7Q, chain A)
Template Kinase: MAPK14
Template inhibitor: quinazolinone compound 2

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPK10CMGC
MAPK8CMGC
MAPK11CMGC
MAPK14CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MAPK10CMGC
MAPK11CMGC
MAPK14CMGC
MAPK8CMGC