Kinase profiling results of kinases in KIF 2ZB0A_GK3 (MAPK14, PDB code: 2ZB0, chain A)
Template Kinase: MAPK14
Template inhibitor: biphenyl amide, 3

5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C
CDK2CMGC    
MAPK10CMGC    
MAPK9CMGC    
MAPK14CMGC    
LCKTK    

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDK2CMGC 
MAPK10CMGC 
MAPK14CMGC 
MAPK9CMGC 
LCKTK