Kinase profiling results of kinases in KIF 3BV2A_P38 (MAPK14, PDB code: 3BV2, chain A)
Template Kinase: MAPK14
Template inhibitor: MLN_518

20 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C
PDPK1AGC      
PRKACAAGC      
CHEK1CAMK      
MARK3CAMK      
CDK2CMGC      
CSNK2A1CMGC      
GSK3BCMGC      
MAPK1CMGC      
MAPK9CMGC      
MAPK11CMGC      
MAPK14CMGC      
PLK1Other      
PLK2Other      
PLK3Other      
ABL1TK      
FGFR1TK      
SRCTK      
HCKTK      
LCKTK      
LYNTK      

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PDPK1AGC    
PRKACAAGC    
CHEK1CAMK    
MARK3CAMK    
CDK2CMGC    
CSNK2A1CMGC    
GSK3BCMGC    
MAPK1CMGC    
MAPK11CMGC    
MAPK14CMGC    
MAPK9CMGC    
PLK1Other    
PLK2Other    
PLK3Other    
ABL1TK    
FGFR1TK    
HCKTK    
LCKTK    
LYNTK    
SRCTK