Kinase profiling results of kinases in KIF 3DT1A_P40 (MAPK14, PDB code: 3DT1, chain A)
Template Kinase: MAPK14
Template inhibitor: DB08351

 18 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C
PDPK1AGC      
CHEK1CAMK      
PRKD2CAMK      
PRKD3CAMK      
CHEK2CAMK      
CDK2CMGC      
MAPK10CMGC      
MAPK8CMGC      
MAPK9CMGC      
MAPK14CMGC      
PLK1Other      
PLK2Other      
PLK3Other      
FGFR1TK      
SRCTK      
LCKTK      
LYNTK      

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
PDPK1AGC     
CHEK1CAMK     
CHEK2CAMK     
PRKD2CAMK     
PRKD3CAMK     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
MAPK10CMGC     
MAPK14CMGC     
MAPK8CMGC     
MAPK9CMGC     
PLK1Other     
PLK2Other     
PLK3Other     
FGFR1TK     
LCKTK     
LYNTK     
SRCTK