Kinase profiling results of kinases in KIF 3FSFA_FSS (MAPK14, PDB code: 3FSF, chain A)
Template Kinase: MAPK14
Template inhibitor: AST_487

 9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPK14CMGC
ABL1TK
FGFR1TK
FGFR2TK
FYNTK
SRCTK
YES1TK
LCKTK
LYNTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MAPK14CMGC
ABL1TK
FGFR1TK
FGFR2TK
FYNTK
LCKTK
LYNTK
SRCTK
YES1TK