Kinase profiling results of kinases in KIF 3GFEA_P37 (MAPK14, PDB code: 3GFE, chain A)
Template Kinase: MAPK14
Template inhibitor: DB08349

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C
CDK2CMGC    
GSK3ACMGC    
MAPK11CMGC    
MAPK12CMGC    
MAPK13CMGC    
MAPK14CMGC    
ABL1TK    
FGFR1TK    
SRCTK    
LCKTK    

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
CDC2CMGC      
CDC2CMGC      
CDK2CMGC      
GSK3ACMGC      
MAPK11CMGC      
MAPK12CMGC      
MAPK13CMGC      
MAPK14CMGC      
ABL1TK      
FGFR1TK      
LCKTK      
SRCTK