Kinase profiling results of kinases in KIF 3HP5A_52P (MAPK14, PDB code: 3HP5, chain A)
Template Kinase: MAPK14
Template inhibitor: VX-745

 12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MAPK11CMGC 
MAPK14CMGC 
ABL1TK 
ABL2TK 
FGRTK 
FYNTK 
SRCTK 
YES1TK 
BLKTK 
HCKTK 
LCKTK 
LYNTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MAPK11CMGC
MAPK14CMGC
ABL1TK
ABL2TK
BLKTK
FGRTK
FYNTK
HCKTK
LCKTK
LYNTK
SRCTK
YES1TK