Kinase profiling results of kinases in KIF 3HVCA_GG5 (MAPK14, PDB code: 3HVC, chain A)
Template Kinase: MAPK14
Template inhibitor: HMS3303H10

 5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK5CMGC
GSK3BCMGC
MAPK9CMGC
NLKCMGC
MAPK14CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CDK5CMGC  
GSK3BCMGC  
MAPK14CMGC  
MAPK9CMGC  
NLKCMGC