Kinase profiling results of kinases in KIF 3MPTA_1GK (MAPK14, PDB code: 3MPT, chain A)
Template Kinase: MAPK14
Template inhibitor: SMR000074150

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
MAPK1CMGC
MAPK14CMGC
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDK2CMGC 
MAPK1CMGC 
MAPK14CMGC 
SRCTK