Kinase profiling results of kinases in KIF 3MVMA_39P (MAPK14, PDB code: 3MVM, chain A)
Template Kinase: MAPK14
Template inhibitor: 39P

 24 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C C
PDPK1AGC       
PRKACAAGC       
CHEK1CAMK       
CDK2CMGC       
CDK5CMGC       
CSNK2A1CMGC       
GSK3ACMGC       
GSK3BCMGC       
MAPK1CMGC       
MAPK8CMGC       
MAPK11CMGC       
MAPK14CMGC       
CHUKOther       
PLK1Other       
PLK2Other       
PLK3Other       
ABL1TK       
FGFR1TK       
SRCTK       
HCKTK       
LCKTK       
LYNTK       
PTK6TK       

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
PDPK1AGC     
PRKACAAGC     
CHEK1CAMK     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK5CMGC     
CSNK2A1CMGC     
GSK3ACMGC     
GSK3BCMGC     
MAPK1CMGC     
MAPK11CMGC     
MAPK14CMGC     
MAPK8CMGC     
CHUKOther     
PLK1Other     
PLK2Other     
PLK3Other     
ABL1TK     
FGFR1TK     
HCKTK     
LCKTK     
LYNTK     
PTK6TK     
SRCTK