Kinase profiling results of kinases in KIF 2NO3A_859 (MAPK8, PDB code: 2NO3, chain A)
Template Kinase: MAPK8
Template inhibitor: 4-anilinopyrimidine 2b

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPKAPK23
CHEK2CAMK
MAPK8CMGC
AURKAOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CHEK2CAMK 
MAPKAPK2CAMK 
MAPK8CMGC 
AURKAOther