Kinase profiling results of kinases in KIF 1NY3A_ADP (MAPKAPK2, PDB code: 1NY3, chain A)
Template Kinase: MAPKAPK2
Template inhibitor: Adenosine-5'-diphosphate

17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
PRKCIAGC
RPS6KA1AGC
RPS6KA1CAMK
STK11CAMK
DAPK1CAMK
MAPKAPK23
PIM1CAMK
CHEK2CAMK
CSNK2A1CMGC
GSK3BCMGC
AURKAOther
NEK2Other
EIF2AK2Other
PLK1Other
STK24STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PDPK1AGC
PRKCIAGC
RPS6KA1AGC
SGK1AGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
PIM1CAMK
STK11CAMK
CSNK2A1CMGC
GSK3BCMGC
AURKAOther
NEK2Other
PLK1Other
STK24STE