Kinase profiling results of kinases in KIF 3A2CA_PDY (MAPKAPK2, PDB code: 3A2C, chain A)
Template Kinase: MAPKAPK2
Template inhibitor: 6-(4-methoxybenzylamino) core C2-substituent, 12

 32 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDC42BPG1 
GRK4AGC 
PDPK1AGC 
PRKCDAGC 
PRKCQAGC 
PRKCEAGC 
PRKCHAGC 
RPS6KB1AGC 
CAMK2DCAMK 
CHEK1CAMK 
SIK2CAMK 
DAPK3CAMK 
STK17ACAMK 
STK17BCAMK 
MAPKAPK23 
MKNK2CAMK 
CHEK2CAMK 
CDK5CMGC 
CSNK2A1CMGC 
DYRK2CMGC 
GSK3BCMGC 
MAPK4CMGC 
AURKAOther 
AURKBOther 
AURKCOther 
SBK1Other 
EIF2AK2Other 
STK36Other 
ULK3Other 
SLKSTE 
STK10STE 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
GRK4AGC   
PDPK1AGC   
PRKCBAGC   
PRKCBAGC   
PRKCDAGC   
PRKCEAGC   
PRKCHAGC   
PRKCQAGC   
RPS6KB1AGC   
CAMK2DCAMK   
CHEK1CAMK   
CHEK2CAMK   
DAPK3CAMK   
MAPKAPK2CAMK   
MKNK2CAMK   
SIK2CAMK   
STK17ACAMK   
CDK5CMGC   
CSNK2A1CMGC   
DYRK2CMGC   
GSK3BCMGC   
AURKAOther   
AURKBOther   
AURKCOther   
ULK3Other   
SLKSTE   
STK10STE