Kinase profiling results of kinases in KIF 3CD8A_L5G (MET, PDB code: 3CD8, chain A)
Template Kinase: MET
Template inhibitor: AMG-208

 5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
EGFRTK 
METTK 
RETTK 
KDRTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CDK2CMGC  
EGFRTK  
KDRTK  
METTK  
RETTK