Kinase profiling results of kinases in KIF 3DKFA_SX8 (MET, PDB code: 3DKF, chain A)
Template Kinase: MET
Template inhibitor: 1-{[6-(pyridin-3-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methyl}-1H-benzimidazole

3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
METTK 
FLT4TK 
KDRTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
FLT4TK 
KDRTK 
METTK