Kinase profiling results of kinases in KIF 3Q6WA_Q6W (MET, PDB code: 3Q6W, chain A)
Template Kinase: MET
Template inhibitor: Pyrrolopyridine, 36

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C
CDK2CMGC     
TNK2TK     
EGFRTK     
INSRTK     
JAK2TK     
JAK3TK     
METTK     
CSF1RTK     
RETTK     
ITKTK     
KDRTK     

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
CDK2CMGC   
CSF1RTK   
EGFRTK   
INSRTK   
ITKTK   
JAK2TK   
JAK3TK   
KDRTK   
METTK   
RETTK   
TNK2TK