Kinase profiling results of kinases in KIF 2XKFA_BX1 (NEK2, PDB code: 2XKF, chain A)
Template Kinase: NEK2
Template inhibitor: 1-[3-Amino-6-(3,4,5-Trimethoxyphenyl)pyrazin-2-Yl]piperidine-4-Carboxylic Acid

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
NEK1Other
NEK2Other
ABL1TK
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
NEK1Other
NEK2Other
ABL1TK
SRCTK