Kinase profiling results of kinases in KIF 2WQNA_ADP (NEK7, PDB code: 2WQN, chain A)
Template Kinase: NEK7
Template inhibitor: Adenosine-5'-diphosphate

 13 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKCIAGC
MAPKAPK23
CDK2CMGC
AURKAOther
NEK2Other
NEK7Other
OXSR1STE
EGFRTK
EPHA3TK
FGFR2TK
MST1RTK
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PRKCIAGC
MAPKAPK2CAMK
CDK2CMGC
AURKAOther
NEK2Other
NEK7Other
OXSR1STE
EGFRTK
EPHA3TK
FGFR2TK
MST1RTK
SRCTK