Kinase profiling results of kinases in KIF 2F57B_23D (PAK7, PDB code: 2F57, chain B)
Template Kinase: PAK7
Template inhibitor: CGP74514A

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
PRKD3CAMK  
CDK2CMGC  
CDK3CMGC  
CDK4CMGC  
PAK4STE  
PAK7STE  
JAK2TK  
JAK3TK  
TXKTK  
NTRK2TK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C C C
PRKD3CAMK         
CDC2CMGC         
CDC2CMGC         
CDK2CMGC         
CDK3CMGC         
CDK4CMGC         
PAK4STE         
PAK7STE         
JAK2TK         
JAK3TK         
NTRK2TK         
TXKTK