Kinase profiling results of kinases in KIF 2XCHA_CKG (PDPK1, PDB code: 2XCH, chain A)
Template Kinase: PDPK1
Template inhibitor: LY_333531

 19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
PDPK1AGC 
MAPKAPK23 
PIM2CAMK 
CDK2CMGC 
CDK4CMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK8CMGC 
MAPK14CMGC 
AURKAOther 
PLK1Other 
PLK2Other 
PLK3Other 
TTKOther 
JAK2TK 
JAK3TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
PDPK1AGC 
MAPKAPK2CAMK 
PIM2CAMK 
CDK2CMGC 
CDK4CMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK14CMGC 
MAPK8CMGC 
AURKAOther 
PLK1Other 
PLK2Other 
PLK3Other 
TTKOther 
JAK2TK 
JAK3TK