Kinase profiling results of kinases in KIF 3H9OA_9BD (PDPK1, PDB code: 3H9O, chain A)
Template Kinase: PDPK1
Template inhibitor: Benzo[c][2,7]naphthyridine, 9

45 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
AKT1AGC  
GRK4AGC  
PDPK1AGC  
PRKCQAGC  
RPS6KB1AGC  
CAMK2DCAMK  
SIK2CAMK  
DAPK3CAMK  
STK17ACAMK  
STK17BCAMK  
DYRK2CMGC  
HIPK4CMGC  
GSK3BCMGC  
MAPK10CMGC  
MAPK9CMGC  
AURKAOther  
AURKBOther  
AURKCOther  
GAKOther  
SBK1Other  
EIF2AK4Other  
EIF2AK2Other  
PLK4Other  
TTKOther  
STK36Other  
ULK3Other  
YSK4STE  
MAP3K2STE  
MAP3K3STE  
SLKSTE  
ABL1TK  
ABL2TK  
CSKTK  
EGFRTK  
ERBB4TK  
EPHA3TK  
EPHA5TK  
EPHB1TK  
FGFR2TK  
JAK2TK  
JAK3TK  
RETTK  
LYNTK  
TXKTK  
IRAK4TKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
AKT1AGC    
GRK4AGC    
PDPK1AGC    
PRKCQAGC    
RPS6KB1AGC    
CAMK2DCAMK    
DAPK3CAMK    
SIK2CAMK    
STK17ACAMK    
DYRK2CMGC    
GSK3BCMGC    
HIPK4CMGC    
MAPK10CMGC    
MAPK9CMGC    
AURKAOther    
AURKBOther    
AURKCOther    
TTKOther    
ULK3Other    
MAP3K2STE    
MAP3K3STE    
SLKSTE    
ABL1TK    
ABL2TK    
CSKTK    
EGFRTK    
EPHA3TK    
EPHA5TK    
EPHB1TK    
ERBB4TK    
FGFR2TK    
JAK2TK    
JAK3TK    
LYNTK    
RETTK    
TXKTK    
IRAK4TKL