Kinase profiling results of kinases in KIF 3QCXA_3Q2 (PDPK1, PDB code: 3QCX, chain A)
Template Kinase: PDPK1
Template inhibitor: HMS3303J20

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PDPK1AGC 
CHEK1CAMK 
CHEK2CAMK 
CDK4CMGC 
MAPK14CMGC 
JAK2TK 
JAK3TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PDPK1AGC 
CHEK1CAMK 
CHEK2CAMK 
CDK4CMGC 
MAPK14CMGC 
JAK2TK 
JAK3TK