Kinase profiling results of kinases in KIF 1YXUA_AMP (PIM1, PDB code: 1YXU, chain A)
Template Kinase: PIM1
Template inhibitor: Adenosine monophosphate

 14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
RPS6KA1AGC
RPS6KA1CAMK
CASKCAMK
DAPK1CAMK
MAPKAPK23
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CSNK2A1CMGC
AURKAOther
NEK2Other
TTKOther
STK24STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AKT2AGC 
GRK6AGC 
RPS6KA1AGC 
CHEK2CAMK 
DAPK1CAMK 
MAPKAPK2CAMK 
PIM1CAMK 
CDK2CMGC 
CSNK2A1CMGC 
AURKAOther 
NEK2Other 
TTKOther 
STK24STE