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Kinase profiling results of kinases in KIF 2C3IB_IYZ
(PIM1, PDB code:
2C3I
, chain B)
Template Kinase: PIM1
Template inhibitor: AC1NURHU
4 kinases in the family
Kinase profiling results source
1. Davis
et al
.
Nature Biotechnology
.
29
, 1046-51
2. Anastassiadis, T.
et al
.
Nature Biotechnology
.
29
, 1039-45
Similarity between template inhibitor and test compounds of profiling results
Atom pair threshold:
0.5
0.6
0.7
0.8
0.9
1
Checkmol threshold:
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
Davis
et al
.
Nature Biotechnology
.
29
, 1046-51
<1nM
>10uM
Kinase
Kinase group
C
PIM1
CAMK
PIM2
CAMK
AURKA
Other
PLK2
Other
Anastassiadis, T.
et al
.
Nature Biotechnology
.
29
, 1039-45
0%
100%
Kinase
Kinase group
PIM1
CAMK
PIM2
CAMK
AURKA
Other
PLK2
Other