Kinase profiling results of kinases in KIF 3BGZA_VX3 (PIM1, PDB code: 3BGZ, chain A)
Template Kinase: PIM1
Template inhibitor: 2,3-diphenyl-1H-indole-7-carboxylic acid

9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
NUAK1CAMK
DAPK1CAMK
PIM1CAMK
PIM2CAMK
PIM3CAMK
CDK2CMGC
CSNK2A1CMGC
CSNK2A2CMGC
CAMKK2Other

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
DAPK1CAMK    
NUAK1CAMK    
PIM1CAMK    
PIM2CAMK    
PIM3CAMK    
CDK2CMGC    
CSNK2A1CMGC    
CSNK2A2CMGC    
CAMKK2Other