Kinase profiling results of kinases in KIF 3CY2A_MB9 (PIM1, PDB code: 3CY2, chain A)
Template Kinase: PIM1
Template inhibitor: AT_7519

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CHEK1CAMK 
DAPK3CAMK 
PIM1CAMK 
CHEK2CAMK 
CDK5CMGC 
CSNK2A1CMGC 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCAAGC 
PRKCBAGC 
PRKCBAGC 
CHEK1CAMK 
CHEK2CAMK 
DAPK3CAMK 
PIM1CAMK 
CDK5CMGC 
CSNK2A1CMGC