Kinase profiling results of kinases in KIF 3CY3A_JN5 (PIM1, PDB code: 3CY3, chain A)
Template Kinase: PIM1
Template inhibitor: JN5

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
RPS6KA3AGC
PIM1CAMK
PIM3CAMK
CDK2CMGC
CSNK2A1CMGC
CSNK2A2CMGC
AURKAOther
AURKBOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
RPS6KA3AGC  
PIM1CAMK  
PIM3CAMK  
CDK2CMGC  
CSNK2A1CMGC  
CSNK2A2CMGC  
AURKAOther  
AURKBOther