Kinase profiling results of kinases in KIF 2VV9A_IM9 (CDK2, PDB code: 2VV9, chain A)
Template Kinase: CDK2
Template inhibitor: 2vv9

19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
AKT1AGC   
AKT2AGC   
PDPK1AGC   
PRKCDAGC   
PRKCQAGC   
CDK2CMGC   
CDK4CMGC   
CDK5CMGC   
CDK9CMGC   
GSK3BCMGC   
MAPK10CMGC   
MAPK14CMGC   
AURKAOther   
AURKBOther   
AURKCOther   
PLK1Other   
PLK2Other   
PLK3Other   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
AKT1AGC   
AKT2AGC   
PDPK1AGC   
PRKCDAGC   
PRKCQAGC   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK4CMGC   
CDK5CMGC   
CDK9CMGC   
GSK3BCMGC   
MAPK10CMGC   
MAPK14CMGC   
AURKAOther   
AURKBOther   
AURKCOther   
PLK1Other   
PLK2Other   
PLK3Other