Kinase profiling results of kinases in KIF 3I5ZA_Z48 (MAPK1, PDB code: 3I5Z, chain A)
Template Kinase: MAPK1
Template inhibitor: Z48

12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
CHEK1CAMK   
CDK2CMGC   
CDC2L6CMGC   
CDK8CMGC   
GSK3BCMGC   
MAPK1CMGC   
MAPK10CMGC   
MAPK14CMGC   
PLK1Other   
PLK2Other   
PLK3Other   
LCKTK   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
CHEK1CAMK   
CDK2CMGC   
GSK3BCMGC   
MAPK1CMGC   
MAPK10CMGC   
MAPK14CMGC   
PLK1Other   
PLK2Other   
PLK3Other   
LCKTK