Kinase profiling results of kinases in KIF 2V55A_ANP (ROCK1, PDB code: 2V55, chain A)
Template Kinase: ROCK1
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
ROCK1AGC
PRKCIAGC
MAPKAPK23
CDK2CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
GRK6AGC
PRKCIAGC
ROCK1AGC
MAPKAPK2CAMK
CDK2CMGC