Kinase profiling results of kinases in KIF 3ACKA_KSR (LCK, PDB code: 3ACK, chain A)
Template Kinase: LCK
Template inhibitor: AC1O6YMO

23 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
NUAK1CAMK
CDK2CMGC
CDK5CMGC
MAPK14CMGC
AURKAOther
NEK2Other
ABL1TK
EGFRTK
FGFR1TK
IGF1RTK
CSF1RTK
KITTK
PDGFRBTK
ROS1TK
SRCTK
YES1TK
LCKTK
PTK6TK
SYKTK
ITKTK
RAF1TKL
TGFBR1TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
NUAK1CAMK   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK5CMGC   
MAPK14CMGC   
AURKAOther   
NEK2Other   
ABL1TK   
CSF1RTK   
EGFRTK   
FGFR1TK   
IGF1RTK   
ITKTK   
KITTK   
LCKTK   
PDGFRBTK   
PTK6TK   
ROS1TK   
SRCTK   
SYKTK   
YES1TK   
RAF1TKL   
TGFBR1TKL