Kinase profiling results of kinases in KIF 3C4FA_C4F (FGFR1, PDB code: 3C4F, chain A)
Template Kinase: FGFR1
Template inhibitor: AC1O6YNE

23 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
NUAK1CAMK
CDK2CMGC
MAPK14CMGC
AURKAOther
AURKBOther
ABL1TK
EGFRTK
PTK2TK
FGFR1TK
IGF1RTK
JAK2TK
CSF1RTK
KITTK
PDGFRBTK
ROS1TK
SRCTK
YES1TK
LCKTK
PTK6TK
SYKTK
TEKTK
KDRTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
NUAK1CAMK      
CDC2CMGC      
CDC2CMGC      
CDK2CMGC      
MAPK14CMGC      
AURKAOther      
AURKBOther      
ABL1TK      
CSF1RTK      
EGFRTK      
FGFR1TK      
IGF1RTK      
JAK2TK      
KDRTK      
KITTK      
LCKTK      
PDGFRBTK      
PTK2TK      
PTK6TK      
ROS1TK      
SRCTK      
SYKTK      
TEKTK      
YES1TK