Kinase profiling results of kinases in KIF 2R5TA_ANP (SGK1, PDB code: 2R5T, chain A)
Template Kinase: SGK1
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
RPS6KA1AGC
RPS6KA1CAMK
CASKCAMK
DAPK1CAMK
MAPKAPK23
CHEK2CAMK
CDK2CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
RPS6KA1AGC
SGK1AGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
CDK2CMGC