Kinase profiling results of kinases in KIF 1YOLA_S03 (SRC, PDB code: 1YOL, chain A)
Template Kinase: SRC
Template inhibitor: QGPSFIYTQAONCS-UHFFFAOYSA-N

30 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PRKCDAGC 
PRKCQAGC 
RPS6KA1AGC 
RPS6KA1CAMK 
CHEK1CAMK 
CDK2CMGC 
ABL1TK 
ALKTK 
CSKTK 
EGFRTK 
ERBB2TK 
EPHB4TK 
FGFR1TK 
IGF1RTK 
INSRTK 
JAK1TK 
JAK2TK 
JAK3TK 
TYK2TK 
KITTK 
PDGFRBTK 
FYNTK 
SRCTK 
YES1TK 
BLKTK 
LCKTK 
LYNTK 
BRAFTKL 
RAF1TKL 
ACVR1TKL 
TGFBR1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PRKCDAGC    
PRKCQAGC    
RPS6KA1AGC    
CHEK1CAMK    
CDK2CMGC    
ABL1TK    
ALKTK    
BLKTK    
CSKTK    
EGFRTK    
EPHB4TK    
ERBB2TK    
FGFR1TK    
FYNTK    
IGF1RTK    
INSRTK    
JAK1TK    
JAK2TK    
JAK3TK    
KITTK    
LCKTK    
LYNTK    
PDGFRBTK    
SRCTK    
TYK2TK    
YES1TK    
ACVR1TKL    
BRAFTKL    
RAF1TKL    
TGFBR1TKL