Kinase profiling results of kinases in KIF 3FQHA_057 (SYK, PDB code: 3FQH, chain A)
Template Kinase: SYK
Template inhibitor: Pyrrole Carboxamide Analog 5c

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CSF1RTK 
LCKTK 
SYKTK 
ITKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CSF1RTK 
ITKTK 
LCKTK 
SYKTK