Kinase profiling results of kinases in KIF 1PY5A_PY1 (TGFBR1, PDB code: 1PY5, chain A)
Template Kinase: TGFBR1
Template inhibitor: LY-364947

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ABL1TK
ABL2TK
LCKTK
RAF1TKL
ACVR1BTKL
TGFBR1TKL
TGFBR2TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ABL1TK   
ABL2TK   
LCKTK   
ACVR1BTKL   
RAF1TKL   
TGFBR1TKL   
TGFBR2TKL