Kinase profiling results of kinases in KIF 3HMMA_855 (TGFBR1, PDB code: 3HMM, chain A)
Template Kinase: TGFBR1
Template inhibitor: DB07267

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ABL1TK
ABL2TK
FYNTK
SRCTK
LCKTK
BMXTK
RAF1TKL
TGFBR1TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
ABL1TK  
ABL2TK  
BMXTK  
FYNTK  
LCKTK  
SRCTK  
RAF1TKL  
TGFBR1TKL