Kinase profiling results of kinases in KIF 3EQPA_T95 (TNK2, PDB code: 3EQP, chain A)
Template Kinase: TNK2
Template inhibitor: 2-aminopyrimidine carbamate, 34

 22 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C
STK33CAMK     
AURKAOther     
ABL1TK     
TNK2TK     
ALKTK     
CSKTK     
EGFRTK     
ERBB2TK     
EPHB4TK     
FGFR1TK     
INSRTK     
JAK2TK     
JAK3TK     
CSF1RTK     
KITTK     
PDGFRBTK     
SRCTK     
HCKTK     
LCKTK     
BTKTK     
ITKTK     
TEKTK     

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
STK33CAMK 
AURKAOther 
ABL1TK 
ALKTK 
BTKTK 
CSF1RTK 
CSKTK 
EGFRTK 
EPHB4TK 
ERBB2TK 
FGFR1TK 
HCKTK 
INSRTK 
ITKTK 
JAK2TK 
JAK3TK 
KITTK 
LCKTK 
PDGFRBTK 
SRCTK 
TEKTK 
TNK2TK