Kinase profiling results of kinases in KIF 2ZMDA_537 (TTK, PDB code: 2ZMD, chain A)
Template Kinase: TTK
Template inhibitor: 1,9-Pyrazoloanthrone

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
RPS6KA2AGC
RPS6KA2CAMK
CAMK1GCAMK
STK33CAMK
DAPK3CAMK
PHKG2CAMK
CDK2CMGC
CDK5CMGC
TTKOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
RPS6KA2AGC      
CAMK1GCAMK      
DAPK3CAMK      
PHKG2CAMK      
STK33CAMK      
CDK2CMGC      
CDK5CMGC      
TTKOther