Kinase profiling results of kinases in KIF 3H9FA_92M (TTK, PDB code: 3H9F, chain A)
Template Kinase: TTK
Template inhibitor: Mps1-IN-2

 12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
RPS6KA1AGC 
RPS6KA1CAMK 
RPS6KA2AGC 
RPS6KA2CAMK 
RPS6KA6AGC 
RPS6KA6CAMK 
STK33CAMK 
DAPK1CAMK 
DAPK3CAMK 
PHKG1CAMK 
PHKG2CAMK 
NEK3Other 
NEK2Other 
TTKOther 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
RPS6KA1AGC 
RPS6KA2AGC 
RPS6KA6AGC 
DAPK1CAMK 
DAPK3CAMK 
PHKG1CAMK 
PHKG2CAMK 
STK33CAMK 
CDC2CMGC 
CDC2CMGC 
NEK2Other 
NEK3Other 
TTKOther