Kinase profiling results of kinases in KIF 2OZOA_ANP (ZAP70, PDB code: 2OZO, chain A)
Template Kinase: ZAP70
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
DAPK1CAMK
CDK2CMGC
AURKAOther
OXSR1STE
STK24STE
MAP2K1STE
MAP2K2STE
EGFRTK
PTK2BTK
FGFR2TK
IGF1RTK
INSRTK
MST1RTK
RETTK
SRCTK
HCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
DAPK1CAMK
CDK2CMGC
AURKAOther
MAP2K1STE
MAP2K2STE
OXSR1STE
STK24STE
EGFRTK
FGFR2TK
HCKTK
IGF1RTK
INSRTK
MST1RTK
PTK2BTK
RETTK
SRCTK
ZAP70TK