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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
1 ACVR1B related diseases
OMIM
(601300)
Pancreatic cancer, somatic
Summary of query kinase
Query kinase
ACVR1B (
P36896
)
Kinase group
TKL
Number of conformation types
0
Number of structural templates
13 (
Total 27 inhibitors
)
Number of ACVR1B related diseases
1 (
OMIM:601300
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
10
2GQGA_1N1
(ABL1)
TKL
Dasatinib
I
74
32
117
A
2GQGA_1N1
(ABL1)
TKL
Dasatinib
I
74
32
117
74
32
117
A
1BYGA_STU
(CSK)
TKL
staurosporine
I
85
72
123
85
72
123
A
2DQ7X_STU
(FYN)
TKL
staurosporine
I
91
74
124
91
74
124
A
2HZ4A_4ST
(ABL1)
TKL
staurosporine
I
159
103
156
159
103
156
A
1PY5A_PY1
(TGFBR1)
TKL
LY-364947
I
7
17
21
7
17
21
A
1OPLA_P16
(ABL1)
TKL
PD166326
I
89
70
123
89
70
123
A
2FO0A_P16
(ABL1)
TKL
PD166326
I
89
70
123
89
70
123
A
2G2HA_P16
(ABL1)
TKL
PD166326
I
89
70
123
89
70
123
A
2HZIA_JIN
(ABL1)
TKL
PD180970
I
90
77
120
90
77
120
A
2X7OA_ZOP
(TGFBR1)
TKL
Imatinib
I
18
43
35
18
43
35
B
3
3D7TA_STU
(CSK)
TKL
staurosporine
I
70
68
99
B
3D7TA_STU
(CSK)
TKL
staurosporine
I
70
68
99
70
68
99
B
2VX1A_7X8
(EPHB4)
TKL
DB07256
I
19
37
15
19
37
15
B
2VWUA_7X1
(EPHB4)
TKL
Chlorobenzod...
I
77
287
111
77
287
111