Summary of query kinase
Query kinase DMPK (Q09013)
Kinase group AGC
Number of inhibitors 45
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 DMPK TG_101348 TG_101348 n/a n/a 1000 n/a n/a NB2011DRx NB2011DRx
1 DMPK AT_7519 AT_7519 n/a n/a 1100 n/a n/a NB2011DRx NB2011DRx
2 DMPK JNJ-7706621 BD00006866 n/a n/a 1200 n/a n/a BindingDB BindingDB
3 DMPK CP_690550 CP_690550 n/a n/a 1200 n/a n/a NB2011DRx NB2011DRx
4 DMPK JNJ_7706621 JNJ_7706621 n/a n/a 1200 n/a n/a NB2008 NB2008
5 DMPK BMS-354825 BD00013216 n/a n/a 1300 n/a n/a BindingDB BindingDB
6 DMPK Dasatinib Dasatinib n/a n/a 1300 n/a n/a NB2008 NB2008
7 DMPK Dasatinib Dasatinib n/a n/a 1300 n/a n/a NB2011DRx NB2011DRx
8 DMPK PP_242 PP_242 n/a n/a 140 n/a n/a NB2011DRx NB2011DRx
9 DMPK Crizotinib Crizotinib n/a n/a 1400 n/a n/a NB2011DRx NB2011DRx
10 DMPK TAE_684 TAE_684 n/a n/a 2100 n/a n/a NB2011DRx NB2011DRx
11 DMPK LY_317615 LY_317615 n/a n/a 2200 n/a n/a NB2011DRx NB2011DRx
12 DMPK CHEMBL603469 BD50308060 n/a n/a 240 n/a n/a BindingDB BindingDB
13 DMPK CEP_701 CEP_701 n/a n/a 240 n/a n/a NB2011DRx NB2011DRx
14 DMPK LY333531 BD00017055 n/a n/a 280 n/a n/a BindingDB BindingDB
15 DMPK LY_333531 LY_333531 n/a n/a 280 n/a n/a NB2008 NB2008
16 DMPK LY_333531 LY_333531 n/a n/a 280 n/a n/a NB2011DRx NB2011DRx
17 DMPK Tarceva BD00005446 n/a n/a 2900 n/a n/a BindingDB BindingDB
18 DMPK BI_2536 BI_2536 n/a n/a 2900 n/a n/a NB2011DRx NB2011DRx
19 DMPK Erlotinib Erlotinib n/a n/a 2900 n/a n/a NB2008 NB2008
20 DMPK Erlotinib Erlotinib n/a n/a 2900 n/a n/a NB2011DRx NB2011DRx
21 DMPK CHEMBL162 BD50059889 n/a n/a 3.5 n/a n/a BindingDB BindingDB
22 DMPK Staurosporine Staurosporine n/a n/a 3.5 n/a n/a NB2008 NB2008
23 DMPK Staurosporine Staurosporine n/a n/a 3.5 n/a n/a NB2011DRx NB2011DRx
24 DMPK cid_451705 BD00031096 n/a n/a 3500 n/a n/a BindingDB BindingDB
25 DMPK INCB18424 INCB18424 n/a n/a 3500 n/a n/a NB2011DRx NB2011DRx
26 DMPK CHEBI:668343 BD50298227 n/a n/a 3800 n/a n/a BindingDB BindingDB
27 DMPK CHEMBL608533 BD50326053 n/a n/a 3800 n/a n/a BindingDB BindingDB
28 DMPK KW_2449 KW_2449 n/a n/a 3800 n/a n/a NB2011DRx NB2011DRx
29 DMPK PKC_412 PKC_412 n/a n/a 3800 n/a n/a NB2008 NB2008
30 DMPK PKC_412 PKC_412 n/a n/a 3800 n/a n/a NB2011DRx NB2011DRx
31 DMPK CHEBI:259924 BD50119072 n/a n/a 59 n/a n/a BindingDB BindingDB
32 DMPK EKB_569 EKB_569 n/a n/a 59 n/a n/a NB2008 NB2008
33 DMPK R547 R547 n/a n/a 610 n/a n/a NB2011DRx NB2011DRx
34 DMPK FLAVOPIRIDOL BD50088605 n/a n/a 650 n/a n/a BindingDB BindingDB
35 DMPK Flavopiridol Flavopiridol n/a n/a 650 n/a n/a NB2008 NB2008
36 DMPK Flavopiridol Flavopiridol n/a n/a 650 n/a n/a NB2011DRx NB2011DRx
37 DMPK Iressa BD00005447 n/a n/a 6900 n/a n/a BindingDB BindingDB
38 DMPK Gefitinib Gefitinib n/a n/a 6900 n/a n/a NB2008 NB2008
39 DMPK Gefitinib Gefitinib n/a n/a 6900 n/a n/a NB2011DRx NB2011DRx
40 DMPK CI_1033 CI_1033 n/a n/a 7000 n/a n/a NB2011DRx NB2011DRx
41 DMPK SKI_606 SKI_606 n/a n/a 91 n/a n/a NB2011DRx NB2011DRx
42 DMPK A_674563 A_674563 n/a n/a 92 n/a n/a NB2011DRx NB2011DRx
43 DMPK BI8 BI8 n/a n/a n/a n/a n/a PDB PDB
44 DMPK CAS62996_74_1 CAS62996_74_1 n/a n/a n/a n/a 4.83 NB2011RBC NB2011RBC